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fosB [2018-05-27 12:22:12]
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fosB [2018-05-27 12:22:12]

bacillithiol-S-transferase; confers resistence against antimicrobial compounds from B. amyloliquefaciens
Locus
BSU17840
Isoelectric point
6.14
Molecular weight
17.03 kDa
Protein length
144 aa Sequence Blast
Gene length
432 bp Sequence Blast
Function
confers resistence against antimicrobial compounds from B. amyloliquefaciens
Product
fosfomycin resistance protein
Essential
no
Synonyms
yndN
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Lifestyles → Coping with stress → Resistance against toxins/ antibiotics
  • Lifestyles → Coping with stress → Cell envelope stress proteins (controlled by SigM, V, W, X, Y)

    • Gene

    Coordinates
    1,916,663 → 1,917,097

    Phenotypes of a mutant

  • sensitive to fosfomycin PubMed

    • The protein

    Protein family

  • FosB subfamily (according to Swiss-Prot)

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    Genes
    fosB
    Description
    PubMed

    Sigma factors

  • SigW: sigma factor, PubMed, in SigW regulon

    • Regulation

  • expressed under stress conditions (SigW) PubMed

    • Additional information

  • A ncRNA is predicted between 'fosB' and 'lexA' PubMed
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    Biological materials

    Mutant

  • MGNA-B387 (yndN::erm), available at the NBRP B. subtilis, Japan
  • BKE17840 (ΔfosB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACAAATCATTCCCCCCTTG, downstream forward: _UP4_TGATAGCACAACCATATTTC
  • BKK17840 (ΔfosB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACAAATCATTCCCCCCTTG, downstream forward: _UP4_TGATAGCACAACCATATTTC

    • References

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